Tuesday, October 11, 2005

On the origins of Glycolysis

Glycolysis requires in its first steps the consumption of 2 molecules of ATP for each molecule of Glycosis to be digested. However such a metabolic pathway could not have emerged as so since it first requires consumption of energy that would be replaced only in later steps that might no exist yet.
Thus the evolution of glycolysis must have been in the inverse order of intake of Gycosis: in the beginning the cells or any previous forms of life used the molecules that were at the most energetic side of glycolysis and as evolution and natural selection acted, ways of converting more abundant species into the ones that could provide energy were developed (as enzymes that could catalyze these reactions).


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